Characteristic	Details
Active Ingredient	Sildenafil Citrate
Dosages Available	25mg, 50mg, 100mg
Onset of Action	30-60 minutes
Duration	4-6 hours
Availability	Learn More

Pharmacokinetics

Fildena 100 mg, powered by sildenafil citrate, plays a crucial role in erectile dysfunction therapy. Once ingested, it acts within 30-60 minutes. Peak plasma concentrations occur around the hour mark. The drug’s bioavailability reaches approximately 41%. Fat-rich meals might slightly delay absorption. This delay can affect onset time, altering patient experience.

Sildenafil’s half-life averages four hours. Metabolism occurs in the liver, primarily by CYP3A4 and CYP2C9 enzymes. The body excretes sildenafil metabolites mainly through feces, with a smaller proportion eliminated via urine. Understanding these dynamics aids in assessing appropriate dosage regimens and timing for users.

Correct Use

Adhering to prescribed guidelines ensures optimal efficacy of Fildena. Consumption occurs with a glass of water, avoiding excessive alcohol or fatty meals before intake. Such substances may hinder drug absorption. A 100 mg dose is common, adjusted according to individual response and tolerance.

Consumption more than once daily is inadvisable. Adjustments for elderly or individuals with hepatic or renal impairment may be necessary. Monitoring by healthcare professionals is essential for these populations. Ensuring proper use enhances therapeutic outcomes and minimizes side effects.

Indications

Fildena 50 mg is predominantly indicated for erectile dysfunction treatment. The mechanism involves inhibiting phosphodiesterase type 5 (PDE5). This inhibition enhances nitric oxide effects, boosting blood flow to penile tissues. The physiological response aids in achieving and maintaining satisfactory erections.

Some off-label uses include pulmonary arterial hypertension management. However, distinct formulations exist for such conditions. Indications must always align with healthcare provider advice. Incorrect usage could lead to adverse health impacts.

Cautions with Other Medicines

Drug interactions can alter Fildena efficacy. Nitrates, often used in cardiovascular disease, may cause severe hypotension if combined with sildenafil. Caution is also necessary with alpha-blockers, antihypertensives, and CYP3A4 inhibitors or inducers.

Consideration of patient medication history is vital. Informing healthcare providers about current prescriptions prevents potential adverse reactions. A comprehensive approach ensures safety and enhances therapeutic benefits.

Adverse Effects

Common side effects of Fildena 25 mg include headaches, flushing, dyspepsia, and dizziness. Most adverse reactions are mild and transient. Persistence or severity requires medical consultation.

Less frequent but serious effects like vision changes, hearing loss, or priapism necessitate immediate attention. Understanding risk factors and contraindications ensures patient well-being during therapy.

Non-prescription availability of Fildena is not standard. Acquisition through legitimate channels ensures product safety and efficacy. Prescription guidance aligns with best clinical practices.

Primary source:

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